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Nucleotides Market

Nucleotides Market Outlook, 2023- Forecasts and Opportunities in the Nucleotides Industry by Nitrogenous Base (Pyrimidine, Purine), Application (Pharmaceuticals, Food, and Beverage Additives, Animal Feed Additives, Diagnostic Research), Companies and Countries to 2030

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  • |Published Month : March, 2023
  • |No. of Pages : 203

Nucleotides Market Share, Trends, and Growth Report 2023

The global nucleotides report is a comprehensive study of the growth opportunities and outlook of nucleotide types and applications across countries. The nucleotides industry analysis provides forecasts of different nitrogenous bases including pyrimidine and purine. Further, market outlook across diverse applications including pharmaceuticals food additives, feed additives, and diagnostic research are provided. The diagnostic research application is further sub-segmented across PCR, NGS, and Hybrid subtypes. Further, the market outlook across 25 countries and the business profiles of 10 leading companies are included in the research study.

Nucleotides Market Study Highlights, 2023

  • The global Nucleotides Market Size stood at $652 million in 2022 and is poised to register 10.95% growth over the forecast period from 2023 to 2030
  • Pyrimidine nitrogenous base is the largest type of nucleotide worldwide, with over 80% market share
  • Diagnostic Research is the largest application segment with 34% market share, followed by food and beverage additives, animal feed, and pharmaceuticals segments
  • Driven by the Chinese market, Asia Pacific dominates the global Nucleotides market with the highest market share
  • Growth in personalized medicine, strong demand for dietary nucleotides, increasing demand from the pharmaceuticals industry, and growth opportunities in emerging economies are the main market-driving forces
  • On the other hand, the possibility of contamination, high costs of manufacturing, and concentrated market conditions restrict the market growth
  • Leading players in the market offer stiff competition to new entrants, small and medium-scale companies.

Nucleotides Market Outlook to 2030

Nucleotides Market Outlook to 2030

Nucleotides Market Overview

Nucleotides are organic molecules that are monomers of DNA, RNA, and other nucleic acids. It comprises a nitrogenous base, a phosphate molecule, and a sugar molecule. In particular, the strong market potential for testing viral diseases supports the market growth during the post-pandemic period.

Wide applications such as animal feeds, seasonings, sweeteners, pharmaceuticals (bulk drugs, intermediates, and formulations), advanced medical materials (oligonucleotides, peptides, proteins, and cell media), cosmetics, and electronic materials encourage the demand for nucleotides worldwide. The report identifies Diagnostics and Research as the largest application segment, driven by wide adoption across countries.

Nucleotides are typically classified into purines and pyrimidines based on the structure of the nitrogenous base. Based on sugar molecules, the nucleotides are categorized as DNA/RNA/others. The nucleic acid comprises a chain of nucleotides linked together with covalent bonds to form a sugar-phosphate backbone with protruding nitrogenous bases. For example, in DNA, purine bases such as adenine and guanine and pyrimidine bases such as thymine and cytosine are included. On the other hand, RNA comprises adenine, guanine, cytosine, and uracil.

Only a few primary manufacturers supply nucleotides worldwide. To stay ahead in the competition, companies market different types such as dNTPs, NTPs, and modified nucleotides in a wide range of formats. Further, to meet the requirements of individual customers, manufacturers also synthesize custom formulations for specific requirements and also market different nucleotide mixes.

Maintaining high purity during the production and purification process by eliminating nucleosidic by-products, residual chemicals, or macromolecule contaminants is essential. Further, functionality testing is also conducted through functional tests such as RT-qPCR and in vitro transcription are conducted.

Manufacturers constantly conduct R&D on the production and application of nucleotides and also explore new production processes. Developing countries such as China, India, South East Asia, Brazil, and other markets offer significant growth opportunities. Ajinomoto Co., Inc., Thermo Fisher Scientific, Biogen, Inc, and other companies are expanding their R&D infrastructure and manpower capabilities, and governments are supporting research activities in genomics and synthetic biology fields.

Flexible packaging including labeling, finishing, and choice of vials and bottles are being marketed by companies. Further, different scales ranging from microliters to liters, milligrams to kilograms are marketed to cater to wide application ranges.

The market is concentrated in nature with CJ CheilJedang Corp, Ajinomoto Co., Inc, Thermo Fisher Scientific, Inc., Star Lake Bioscience Co., Inc. Zhaoqing Guangdong, Daesang Corporation, and other companies dominating the industry. These five companies are analyzed in the report.

Nucleotides Market Trend - Strong demand for dietary nucleotides

Dietary nucleotides are one of the potential market segments as food and beverage companies are widely marketing the products.

Health benefits offered by the products such as muscle growth/contraction, protein synthesis, proliferation, metabolism, live function, and others are encouraging demand for nucleotides in the food and beverages industry.

Contribution to the reinforcement of immune response is largely promoted during the COVID-19 pandemic, which supported the sales of the products worldwide in the segment.

Nucleotides Market Restraints- High costs of manufacturing

The industry is witnessing a strong surge of interest and momentum with regulatory approvals and multiple late-stage pipeline products of medicines. However, the design and construction of these medicines at a commercial scale involve high costs. The transition from laboratories to large-scale processes involves significant costs, design, and development challenges. Further, amidst fears of contamination, upstream processing such as synthesis, cleavage, and deprotection, and downstream processing sequences such as purifying, achieving required concentration levels, and freeze-drying the substance requires significant costs. Due to high complexities such as side effects, drugs using nucleotides have been withdrawn, which results in significant investment losses.

Nucleotides Market Share Analysis- Pharmaceuticals held the dominant revenue-generating segment

The strong advent of personalized medicine where drugs are tailored to patient's needs based on their genetic information is encouraging investments in the adoption of nucleotides in the pharmaceuticals industry.

Nucleotide-based medicines use nucleotides to target cellular genetic information directly. The huge potential of nucleotide-based medicines is driving collaborations in the industry. Purine and pyrimidine analogs comprising halogens, thiols, and others are widely used in cancer treatment, suppressing target cells and others. Substrate analogs of nucleotide metabolizing enzymes and modified nucleotides are being assessed for treatment against multiple conditions.

To assess the potential of nucleotides in the treatment of several pathologies and infections, companies are forming collaborations with universities, companies, and other institutes. Dietary Supplements, Baby formula, medication for diverse conditions, and others are widely being formulated worldwide.

Nucleotides Market Share- Pharmaceuticals, Food Additives, Feed Additives, Diagnostic Research

Enzyme regulation, metabolism regulation, protein synthesis, and other functions are performed by nucleotides. When linked with vitamin derivatives, they form a portion of coenzymes (coenzyme A, NAD, NADP, and FAD), and as donors and acceptors of phosphoryl groups in energy transduction processes.

Nucleoside-lipid derivatives act as intermediates in lipid biosynthesis. They also play a vital role in metabolic regulation. Further, Deoxynucleoside triphosphates (dNTPs) and nucleoside triphosphates (NTPs) serve as the immediate substrates for the biosynthesis of DNA and RNA, respectively.

The role of nucleotides in drug discovery also remains significant, predominantly in mRNA vaccines, antiviral drugs, and cytostatic nucleotides (substrate analogs of physiological nucleotides that inhibit cell proliferation by interfering with cellular targets involved in DNA/RNA synthesis and nucleotide metabolism).

Nucleotides Market Segmentation

Nitrogenous Base

  • Pyrimidine 
  • Purine

Applications

  • Pharmaceuticals
  • Food & Beverage Additives
  • Animal Feed Additives
  • Diagnostic Research
    • PCR
    • NGS
    • Hybrid

Regions

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East and Africa

1. Executive Summary

1.1 Introduction to Nucleotides Markets

1.2 Nucleotides Market Size Outlook, 2021- 2030

1.3 Growth Opportunities in Nucleotides Industry

1.4 Winning Strategies for the post-pandemic future

 

2. Report Guide

2.1 Market Definition and Scope

2.2 Market Segmentation

2.3 Research Methodology

2.4 Forecast Methodology

2.5 List of Abbreviations

 

3. Growth Opportunity Analysis

3.1 Key Nucleotides Market Trends

3.1.1 Growth in personalized medicine

3.1.2 Strong demand for dietary nucleotides

 

3.2 Key Nucleotides Market Growth Drivers

3.2.1 Increasing demand from the Pharmaceutical industry

3.2.2 Diagnostic Research Investments

 

3.3 Key Nucleotides Market Growth Restraints

3.3.1 High costs of manufacturing

3.3.2 Possibility of Contamination

 

4 Nucleotides Market Outlook – Scenario Analysis

4.1 Low Growth Case Scenario Forecasts: Nucleotides Market Size Outlook to 2030

4.2 Reference Growth Case Scenario Forecasts: Nucleotides Market Size Outlook to 2030

4.3 High Growth Case Scenario Forecasts: Nucleotides Market Size Outlook to 2030

 

5. Nucleotides Market Segmentation- Outlook by Nitrogenous Base

5.1 Nucleotides Market Share Analysis by Nitrogenous Base, 2023

5.2 Pyrimidine Market Outlook to 2030

5.3 Purine Market Outlook to 2030

 

6. Nucleotides Market Segmentation- Outlook by Application

6.1 Nucleotides Market Share Analysis by Application, 2023

6.2 Pharmaceuticals: Nucleotides Market Outlook to 2030

6.3 Food & Beverage Additives: Nucleotides Market Outlook to 2030

6.4 Animal Feed Additives Nucleotides Market Outlook to 2030

6.5 Diagnostic Research: Nucleotides Market Outlook to 2030

 

7. Diagnostic Research Market Segmentation- Outlook by Sub-Type

7.1 Diagnostic Research Market Share Analysis by Sub-Type, 2023

7.2 PCR: Nucleotides Market Outlook to 2030

7.3 NGS: Nucleotides Market Outlook to 2030

7.4 Hybrid: Nucleotides Market Outlook to 2030

 

8. North America Nucleotides Market Outlook and Opportunities to 2030

8.1 Market Snapshot, 2023

8.2 North America Nucleotides Market Growth Opportunities

8.2.1 North America Nucleotides Market Outlook by Type, 2021 to 2030

8.2.2 North America Nucleotides Market Outlook by Application, 2021 to 2030

8.2.3 North America Nucleotides Market Outlook by Country, 2021 to 2030

8.3 United States Nucleotides Market Outlook, 2021 to 2030

8.4 Canada Nucleotides Market Outlook, 2021 to 2030

8.5 Mexico Nucleotides Market Outlook, 2021 to 2030

 

9. Europe Nucleotides Market Outlook and Opportunities to 2030

9.1 Market Snapshot, 2023

9.2 Europe Nucleotides Market Growth Opportunities

9.2.1 Europe Nucleotides Market Outlook by Type, 2021 to 2030

9.2.2 Europe Nucleotides Market Outlook by Application, 2021 to 2030

9.2.3 Europe Nucleotides Market Outlook by Country, 2021 to 2030

9.3 Germany Nucleotides Market Outlook, 2021 to 2030

9.4 France Nucleotides Market Outlook, 2021 to 2030

9.5 United Kingdom Nucleotides Market Outlook, 2021 to 2030

9.6 Spain Nucleotides Market Outlook, 2021 to 2030

9.7 Italy Nucleotides Market Outlook, 2021 to 2030

9.8 Other Europe Nucleotides Market Outlook, 2021 to 2030

 

10. Asia Pacific Nucleotides Market Outlook and Opportunities to 2030

10.1 Market Snapshot, 2023

10.2 Asia Pacific Nucleotides Market Growth Opportunities

10.2.1 Asia Pacific Nucleotides Market Outlook by Type, 2021 to 2030

10.2.2 Asia Pacific Nucleotides Market Outlook by Application, 2021 to 2030

10.2.3 Asia Pacific Nucleotides Market Outlook by Country, 2021 to 2030

10.3 China Nucleotides Market Outlook, 2021 to 2030

10.4 Japan Nucleotides Market Outlook, 2021 to 2030

10.5 India Nucleotides Market Outlook, 2021 to 2030

10.6 South Korea Nucleotides Market Outlook, 2021 to 2030

10.7 Indonesia Nucleotides Market Outlook, 2021 to 2030

10.8 Other Asia Pacific Nucleotides Market Outlook, 2021 to 2030

 

11. South and Central America Nucleotides Market Outlook and Opportunities to 2030

11.1 Market Snapshot, 2023

11.2 South and Central America Nucleotides Market Growth Opportunities

11.2.1 South and Central America Nucleotides Market Outlook by Type, 2021 to 2030

11.2.2 South and Central America Nucleotides Market Outlook by Application, 2021 to 2030

11.2.3 South and Central America Nucleotides Market Outlook by Country, 2021 to 2030

11.3 Brazil Nucleotides Market Outlook, 2021 to 2030

11.4 Argentina Nucleotides Market Outlook, 2021 to 2030

11.5 Other Latin America Nucleotides Market Outlook, 2021 to 2030

 

12. Middle East and Africa Nucleotides Market Outlook and Opportunities to 2030

12.1 Market Snapshot, 2023

12.2 Middle East and Africa Nucleotides Market Growth Opportunities

12.2.1 Middle East and Africa Nucleotides Market Outlook by Type, 2021 to 2030

12.2.2 Middle East and Africa Nucleotides Market Outlook by Application, 2021 to 2030

12.2.3 Middle East and Africa Nucleotides Market Outlook by Country, 2021 to 2030

12.3 Saudi Arabia Nucleotides Market Outlook, 2021 to 2030

12.4 United Arab Emirates (the UAE) Nucleotides Market Outlook, 2021 to 2030

12.5 Other Middle East Nucleotides Market Outlook, 2021 to 2030

12.6 Egypt Nucleotides Market Outlook, 2021 to 2030

12.7 South Africa Nucleotides Market Outlook, 2021 to 2030

12.8 Other Africa Nucleotides Market Outlook, 2021 to 2030

 

13. Profiles of major world Nucleotides Companies

13.1 CJ CheilJedang Corp

- Key Statistics

- Business Operations

- Products and Services Offered

- SWOT Analysis

- Financial Profile

13.2 Ajinomoto Co., Inc

- Key Statistics

- Business Operations

- Products and Services Offered

- SWOT Analysis

- Financial Profile

13.3 Thermo Fisher Scientific, Inc

- Key Statistics

- Business Operations

- Products and Services Offered

- SWOT Analysis

- Financial Profile

13.4 Star Lake Bioscience Co., Inc

- Key Statistics

- Business Operations

- Products and Services Offered

- SWOT Analysis

- Financial Profile

13.5 Daesang Corporation

- Key Statistics

- Business Operations

- Products and Services Offered

- SWOT Analysis

- Financial Profile

13.6 Jena Bioscience GmbH

- Key Statistics

- Business Operations

- Products and Services Offered

- SWOT Analysis

- Financial Profile

13.7 MeiHua Holdings Group Co., Ltd

- Key Statistics

- Business Operations

- Products and Services Offered

- SWOT Analysis

- Financial Profile

13.8 Meridian Bioscience

- Key Statistics

- Business Operations

- Products and Services Offered

- SWOT Analysis

- Financial Profile

- Financial Profile

13.9 Star Lake Bioscience Co, Inc.

- Key Statistics

- Business Operations

- Products and Services Offered

- SWOT Analysis

- Financial Profile

- Financial Profile

 

14. Appendix

14.1 Publisher’s Expertise

14.2 List of Tables and Charts

14.3 List of Exhibits

14.4 Legal Disclaimer   

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